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Melasma emulsion8/20/2023 Retin-A, aka tretinoin, has been clinically shown to increase cell turnover and stimulate collagen growth, encouraging fresh new skin with a more even tone and smoother texture.Tyrosinase is the enzyme that catalyzes the production of melanin, so inhibiting the activation of tyrosinase reduces the amount of melanin synthesized and carried to the superficial layers of the skin. Sacha Obaid, a plastic surgeon in Southlake, Texas. “The Cosmelan peel penetrates deep into the skin, to decrease the natural production of the tyrosinase enzyme,” says Dr. Cosmelan 2’s active ingredients are titanium dioxide, kojic acid, phytic acid, and ascorbic acid. Active ingredients in Cosmelan 1 include azelaic acid, kojic acid, phytic acid, ascorbic acid, arbutin, and titanium dioxide. Both the peel (Cosmelan 1) and cream (Cosmelan 2) contain ingredients that suppress melanin production. Cosmelan is a system that combines an in-office chemical peel and an at-home cream.These are the melasma treatment options that doctors and RealSelf members say work best.ġ–12 days of downtime (depending on intensity) Results from even the best treatments won't hold if patients don’t apply (and reapply) sunscreen with an SPF of 30+ every day. Improving melasma requires ongoing professional and topical treatments, in combination with diligent sunscreen use and sun avoidance. Even patches that seem to fade completely almost always come back. There is no cure for melasma, so the condition never fully resolves. Unfortunately, all the most effective melasma treatments carry risks of triggering more hyperpigmentation or hypopigmentation (spots that lose pigment and appear lighter than the rest of the skin), so it’s important to ease in, with an abundance of caution, to prevent potential remedies from backfiring and worsening your condition. If you have olive or brown skin, it’s essential to find a dermatologist who’s experienced in treating dark skin tones. Removing old layers of the skin makes room for fresh, healthy cells and brings trapped pigment to the surface so it can be shed. Treatments to improve the appearance of melasma focus on releasing the excess pigment from the skin and encouraging cell turnover. Other factors, like heat, visible light, thyroid disease, and stress, can contribute to or exacerbate melasma. Nissan Pilest, a dermatologic surgeon in Irvine, California. “Sun exposure will immediately ramp up the pigment production, if you aren't protected with a full-spectrum sunscreen,” says Dr. Sun exposure. Sun can both bring on melasma and worsen existing patches, since UV light speeds up melanin production.However, most melasma treatments are not safe for women who are pregnant or breastfeeding. Birth control pills and hormone replacement therapies can trigger it as well. Often dubbed “the mask of pregnancy,” the skin condition is especially common in pregnant women, whose estrogen and progesterone levels overstimulate melanin production. According to the American Academy of Dermatology, 90% of people who get melasma are women. Unlike postinflammatory hyperpigmentation, which is caused by injury or irritation (like acne, eczema, or bug bites), melasma is typically triggered by two main risk factors: hormonal changes and UV radiation from sunlight.
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